L-Arginine

Arginine is the original basis of congestion formulas, the ingredient upon which an entire generation of boosters was built. This section brings together pure L-arginine, AAKG, and cell volume supplements, available in both bulk powder and capsules. For athletes who formulate their own pre-workout and want to control every gram.

IO Genix Arginine Kyowa
IO Genix Arginine Kyowa - L-arginine pure en poudre
IO.GENIX

IO Genix Arginine Kyowa

(2)

23,90 €

Sinob Core AAKG L-Arginine
Sinob Core AAKG L-Arginine, superior absorption for the pump
Sinob

Sinob Core AAKG L-Arginine

(0)

29,90 €

OstroVit A-AKG 200 g
OstroVit A-AKG 200 g — Nature
OstroVit A-AKG 200 g — Citron
OstroVit A-AKG 200 g — Orange
OstroVit

OstroVit A-AKG 200 g

(0)

13,90 €

Applied Nutrition L-Arginine 1500
Flacon d'Applied Nutrition L-Arginine 1500, 120 gélules végétales
APPLIED NUTRITION

Applied Nutrition L-Arginine 1500

(0)

23,90 €

Now Foods Arginine et Ornithine
NOW Foods Arginine et Ornithine — 250 gélules
Now Foods Arginine et Ornithine 250 gélules
Now Foods Arginine Ornithine - vue de droite
NOW Foods

Now Foods Arginine et Ornithine

(0)

From 19,04 €

Now Foods L-Arginine 1000 mg Comprimés
Now Foods L-Arginine 1000 mg comprimés
Now Foods L-Arginine 1000 mg comprimés - vue de droite
Now Foods L-Arginine 1000 mg comprimés - vue de gauche
NOW Foods

Now Foods L-Arginine 1000 mg Comprimés

(0)

From 17,60 €

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What is the effect of L-arginine in the body?

L-arginine is a semi-essential amino acid: the body can produce it, but not always in sufficient quantities, especially during growth or significant physiological stress. It is obtained through diet from meat, fish, dairy products, nuts, and legumes.

Its most discussed effect in sports nutrition involves the nitric oxide pathway. The NO-synthase enzyme converts arginine into nitric oxide, a gaseous molecule that relaxes blood vessel walls and increases local blood flow. This mechanism explains the presence of arginine in almost all "pump" pre-workouts: more blood in the muscle during exertion, leading to greater congestion, and theoretically better delivery of oxygen and nutrients.

Arginine is also involved elsewhere. It is a link in the urea cycle, the pathway by which the body eliminates nitrogen from protein metabolism. It serves as a precursor to endogenous creatine and polyamines involved in cell renewal. Finally, it participates in hormonal secretion mechanisms, which fueled extensive literature on growth hormone in the 1990s—literature whose practical conclusions for a healthy individual proved to be much less significant than announced.

These roles are real at the physiological level. The question that matters to a consumer is different: what happens when you take arginine in powder or capsule form?

Why is citrulline more effective orally?

It must be said clearly, even if it leads some readers to another section: to raise blood arginine levels, citrulline works better than arginine itself. Two obstacles explain this paradox.

The first is the first-pass effect. Ingested arginine is massively taken up by the intestine and liver before reaching general circulation. A significant portion of the dose is metabolized on site, and what actually reaches the muscle is much less than what the label measurement suggests.

The second is arginase, an enzyme abundant in the intestine and liver, which degrades arginine into ornithine and urea. The higher the oral dose, the more this pathway is used. This is why increasing the dose does not solve the problem: it primarily feeds the enzyme responsible for destroying it.

Citrulline, on the other hand, avoids both. It is not a substrate of arginase and passes through the liver without being taken up; it is then converted to arginine by the kidney, downstream of these obstacles. The counter-intuitive but well-established result: a given dose of citrulline increases plasma arginine levels more and more durably than the same dose of arginine. If your goal is pump during training, you should turn to our citrulline section, with 6 to 8 g before your session, and not to arginine.

In what cases does L-arginine still have an interest?

This superiority of citrulline does not make arginine useless. Three uses remain defensible.

AAKG and salt forms. Arginine alpha-ketoglutarate combines the amino acid with alpha-ketoglutarate, an intermediate of the Krebs cycle. Forms like AAKG or arginine HCl aim for better stability and more consistent absorption. The difference with free arginine remains modest, but these forms constitute a classic and well-tolerated basis for pump formulas, often alongside citrulline rather than in its place.

High doses. Protocols showing a measurable effect on plasma arginine use 3 to 6 g, sometimes more. Below 3 g, the first-pass effect absorbs almost the entire dose. A formula announcing 500 mg of arginine per serving checks a marketing box, nothing more.

Non-sporting contexts. Arginine is used in medical settings in situations of increased needs, and it is found in pharmacies in various forms, often combined with other active ingredients. These uses require a prescription and monitoring: they do not translate to self-decided workout supplementation, and we do not enter this field.

A word about a related ingredient, often associated with arginine in pump formulas: glycerol, which does not act on nitric oxide but retains water in the vascular and muscular compartments. It is a supplement, not a substitute. Our caffeine-free boosters frequently combine these two approaches.

What are the dangers of L-arginine?

The question of the dangers of L-arginine deserves a precise answer rather than a reassuring statement. At dietary doses, this amino acid is consumed daily by everyone without difficulty. At supplementation doses, a few points deserve real attention.

Digestive disorders. This is the most common side effect, and it is dose-dependent. Beyond 5 to 10 g in a single dose, nausea, bloating, abdominal cramps, and diarrhea become common. The mechanism is partly osmotic: a large load of free amino acid in the intestine draws water. Splitting the dose and taking it with some food limits the problem.

Interactions with vasodilators and antihypertensive treatments. This is the most important point, and it is not theoretical. Arginine acts on the same pathway as several classes of medications: nitrates, antihypertensive treatments, PDE5 inhibitors. The addition of two vasodilatory effects can cause blood pressure to drop beyond what is desirable. If you are on any of these treatments, the question must be posed to your doctor or pharmacist before starting, not after.

Herpes. The HSV virus uses arginine for its replication, and the ratio between arginine and lysine in the diet is a factor discussed in the occurrence of outbreaks. The data is not definitive, but if you are prone to recurrent outbreaks, this is something to consider and discuss with your doctor before prolonged high-dose supplementation.

Kidney and liver pathologies. Arginine is part of the urea cycle, which the liver and kidneys ensure functions and eliminates products. In cases of kidney or liver failure, an additional load of amino acids is not trivial and requires medical advice.

Specific situations. Pregnancy and breastfeeding, post-infarction period, severe asthma, and ongoing treatments in general: caution involves seeking advice from a healthcare professional rather than relying on a label. There is nothing alarming for a healthy adult who respects the doses, but nothing that justifies ignoring these situations either. European evaluations of amino acids in dietary supplements are the responsibility of the EFSA, and French recommendations are from ANSES.

What dose and when?

For training-related use, the useful range is between 3 and 6 g, taken 45 to 60 minutes before the session — a longer delay than for citrulline, whose peak is later but pathway is more direct. AAKG forms are used in the same range.

Start with 3 g to assess your digestive tolerance before going higher. Beyond 6 g in a single dose, the discomfort-to-benefit ratio significantly deteriorates.

If you are already taking citrulline, there is no reason to add a high dose of arginine on top: both feed the same pathway, and the latter is the less effective of the two orally. Conversely, arginine combines easily with ingredients that act through other mechanisms: beta-alanine for acid buffering, electrolytes for hydration, EAAs during training.

Frequently Asked Questions

What is L-arginine?

A semi-essential amino acid: the body can produce it, but not always in sufficient quantities during growth or significant physiological stress. The "L-" prefix simply denotes the natural form, the one found in dietary proteins. As a supplement, it comes as pure powder, capsules, or in salt form such as arginine HCl and AAKG. Its most commented role in sports nutrition is to be the direct precursor of nitric oxide, the molecule that relaxes blood vessel walls and increases local blood flow.

What are the benefits of L-arginine?

First, it's important to state what doesn't exist: no health claims are authorized in Europe for arginine, as none have passed evaluation by the EFSA. What is documented pertains to physiology, not promised benefits. It is the substrate for NO-synthase, and thus for nitric oxide and vasodilation; it is a link in the urea cycle, through which nitrogen from proteins is eliminated; it serves as a precursor to endogenous creatine and polyamines involved in cell renewal. Useful to know, but insufficient to promise a specific outcome.

What effects does L-arginine have?

Honestly, very little, and this is what often leads to disappointment. The only noticeable effect is sometimes a slightly more pronounced pump during training, with doses of 3 to 6 g taken 45 to 60 minutes beforehand: veins become more visible, muscles appear fuller. The sensation is real but modest, and many cannot distinguish it from a placebo. No stimulating effect, no energy boost, no strength gain: in this regard, creatine monohydrate remains the benchmark supplement.

When should I take arginine?

45 to 60 minutes before your workout if your goal is muscle pump—a longer delay than for citrulline, allowing time for the fraction escaping the liver to reach circulation. On an empty stomach or away from a protein-rich meal is preferable: other amino acids compete for the same intestinal transporters. Outside of training, no specific time has shown particular benefit, including evening intake sometimes presented as favorable for growth hormone: protocols showing this effect used intravenous doses unrelated to a capsule.

How much arginine per day?

Between 3 and 6g per dose for training-related use. Below 3g, the intestine and liver capture almost the entire dose, and nothing measurable happens—formulas displaying 500mg per serving check a marketing box. Beyond 6g in a single dose, digestive comfort significantly deteriorates without additional benefit, as the enzyme that degrades arginine is simply more active. Start at 3g to assess your tolerance, and don't forget to account for the arginine already present in your booster.

What are the dangers of arginine?

At dietary doses, none: everyone consumes it daily. At supplementation doses, four points deserve real attention. First, digestive issues—nausea, bloating, diarrhea beyond 5 to 10 g in a single dose. Second, drug interactions, and this is the most important point: arginine acts on the same pathway as nitrates, antihypertensives, and PDE5 inhibitors, and the addition of two vasodilatory effects can cause blood pressure to drop—ask your doctor before, not after. Third, herpes: the virus uses arginine to replicate, a factor to consider in cases of recurrent outbreaks. Finally, kidney or liver failure, as arginine is part of the urea cycle. Pregnancy, breastfeeding, and ongoing treatments fall under the same precautionary principle.

Is L-arginine a vasodilator?

Indirectly. It is the substrate that NO-synthase converts into nitric oxide, which relaxes the smooth muscle of the vascular wall and increases local blood flow: it is not the arginine itself that dilates, but its raw material. Two nuances are important. The oral route is not efficient, as the intestine and liver capture most of the dose before it reaches circulation. And it is precisely this vascular action that dictates the main precaution for the product: never add it to a vasodilator or antihypertensive treatment without medical advice.

Does arginine cause weight gain?

No. A dose of 3 to 6 g provides twelve to twenty kilocalories, an amount without effect on the day's energy balance. The only weight variation sometimes observed with pump formulas comes from water retained by glycerol or creatine that accompanies them, not from arginine, and it disappears upon discontinuation.

Does arginine make you grow taller?

No, and this confusion must be cleared up directly. The idea comes from studies in the 1990s showing that a high-dose intravenous infusion of arginine causes a transient peak of growth hormone—a test used in endocrinology, not an effect reproducible with a capsule. Orally, the elevation is small, brief, and has no demonstrated consequence on height, muscle mass, or recovery. Adult height depends on genetics, overall nutrition during growth, and hormonal status: no dietary supplement modifies it. For children and adolescents, these products are not indicated, and any growth-related questions should be addressed to a doctor.

Where can I find arginine, and which food contains the most?

The densest sources are not what you might expect: pumpkin seeds, peanuts, almonds, walnuts, and sesame seeds contain proportionally more than meat. Next are turkey, chicken, pork, fish, dairy products, soy, chickpeas, and lentils. A typical diet provides several grams per day, which is largely sufficient for a healthy adult. The Ciqual database details the amino acid composition food by food.

What is the value of arginine sold in pharmacies?

It's the same amino acid, obtained through the same fermentation processes. Differences lie in the galenic form—sachets, ampoules, capsules—, the dosage per unit, and associations with other active ingredients, which often drive up the price per gram. Some presentations are also medicinal products, with their own indications and follow-up: they do not translate to self-decided training supplementation. Compare the actual amount of arginine per dose and the price per gram, rather than the distribution channel.

L-arginine or citrulline, which to choose?

Citrulline, in almost all cases where the goal is muscle pump during training. It raises blood arginine levels more than arginine itself, for the reasons explained above. Arginine still has its place in combined formulas and in AAKG form.

Can it be combined with a booster?

Yes, provided the doses are added up. Many pump formulas already contain arginine or AAKG: check the label before adding more, just as you would for citrulline. The boosters section and our selection of creatine-free pre-workouts detail how to read a nutritional label.

What forms of arginine do we offer?

Our selection covers both approaches. IO.Genix offers Kyowa quality arginine, a fermentation manufacturing benchmark, for those who want the amino acid alone and well-identified. Sinob offers the AAKG version, intended for pump formulas. Peak Performance Nutrition completes the range with liquid glycerol, which acts on cell volume through a distinct mechanism and combines well with an arginine or citrulline base.

If your goal is purely pump, the honest comparison remains with the citrulline section, which is more effective at equal doses and generally better tolerated digestively.

Discuss near Montpellier

Our store in Vendargues, about ten minutes from Montpellier, allows you to ask questions that don't belong in a product sheet, starting with questions about ongoing treatments. We prefer to suggest another product, or recommend consulting your doctor, rather than selling a supplement that isn't suitable for your situation. We also ship throughout France and Europe.

View Store
Now Foods L-Arginine 500 mg Gélules
Now Foods L-Arginine 500 mg 100 gélules
NOW Foods L-Arginine 500 mg 250 gélules
NOW Foods

Now Foods L-Arginine 500 mg Gélules

(0)

From 11,95 €

Now Foods Arginine et Citrulline
Now Foods Arginine et Citrulline 120 gélules
NOW Foods Arginine et Citrulline — 240 gélules
NOW Foods

Now Foods Arginine et Citrulline

(0)

From 21,94 €

Now Foods L-Arginine Pure en Poudre — 454 g
NOW Foods L-Arginine pure en poudre, pot de 454 g
NOW Foods

Now Foods L-Arginine Pure en Poudre — 454 g

(0)

41,27 €

Skill Nutrition L-Arginine 1600 mg
Skill Nutrition L-Arginine 1600 mg
Skill Nutrition L-Arginine 1600 mg — autre vue
Skill Nutrition

Skill Nutrition L-Arginine 1600 mg

(0)

13,90 €

Retrait au magasin sous 2 h

À Vendargues, près de Montpellier. Vous êtes prévenu dès que la commande est prête.

Commandé avant 14 h, expédié le jour même

Du lundi au samedi. Le délai d'acheminement appartient ensuite au transporteur.

Livraison offerte dès 69 €

En France métropolitaine, et dès 100 € en Europe. Modes et délais.

Une question avant de commander ?

Écrivez-nous ou passez au magasin : on connaît les produits qu'on vend.

What is the effect of L-arginine in the body?

L-arginine is a semi-essential amino acid: the body can produce it, but not always in sufficient quantities, especially during growth or significant physiological stress. It is obtained through diet from meat, fish, dairy products, nuts, and legumes.

Its most discussed effect in sports nutrition involves the nitric oxide pathway. The NO-synthase enzyme converts arginine into nitric oxide, a gaseous molecule that relaxes blood vessel walls and increases local blood flow. This mechanism explains the presence of arginine in almost all "pump" pre-workouts: more blood in the muscle during exertion, leading to greater congestion, and theoretically better delivery of oxygen and nutrients.

Arginine is also involved elsewhere. It is a link in the urea cycle, the pathway by which the body eliminates nitrogen from protein metabolism. It serves as a precursor to endogenous creatine and polyamines involved in cell renewal. Finally, it participates in hormonal secretion mechanisms, which fueled extensive literature on growth hormone in the 1990s—literature whose practical conclusions for a healthy individual proved to be much less significant than announced.

These roles are real at the physiological level. The question that matters to a consumer is different: what happens when you take arginine in powder or capsule form?

Why is citrulline more effective orally?

It must be said clearly, even if it leads some readers to another section: to raise blood arginine levels, citrulline works better than arginine itself. Two obstacles explain this paradox.

The first is the first-pass effect. Ingested arginine is massively taken up by the intestine and liver before reaching general circulation. A significant portion of the dose is metabolized on site, and what actually reaches the muscle is much less than what the label measurement suggests.

The second is arginase, an enzyme abundant in the intestine and liver, which degrades arginine into ornithine and urea. The higher the oral dose, the more this pathway is used. This is why increasing the dose does not solve the problem: it primarily feeds the enzyme responsible for destroying it.

Citrulline, on the other hand, avoids both. It is not a substrate of arginase and passes through the liver without being taken up; it is then converted to arginine by the kidney, downstream of these obstacles. The counter-intuitive but well-established result: a given dose of citrulline increases plasma arginine levels more and more durably than the same dose of arginine. If your goal is pump during training, you should turn to our citrulline section, with 6 to 8 g before your session, and not to arginine.

In what cases does L-arginine still have an interest?

This superiority of citrulline does not make arginine useless. Three uses remain defensible.

AAKG and salt forms. Arginine alpha-ketoglutarate combines the amino acid with alpha-ketoglutarate, an intermediate of the Krebs cycle. Forms like AAKG or arginine HCl aim for better stability and more consistent absorption. The difference with free arginine remains modest, but these forms constitute a classic and well-tolerated basis for pump formulas, often alongside citrulline rather than in its place.

High doses. Protocols showing a measurable effect on plasma arginine use 3 to 6 g, sometimes more. Below 3 g, the first-pass effect absorbs almost the entire dose. A formula announcing 500 mg of arginine per serving checks a marketing box, nothing more.

Non-sporting contexts. Arginine is used in medical settings in situations of increased needs, and it is found in pharmacies in various forms, often combined with other active ingredients. These uses require a prescription and monitoring: they do not translate to self-decided workout supplementation, and we do not enter this field.

A word about a related ingredient, often associated with arginine in pump formulas: glycerol, which does not act on nitric oxide but retains water in the vascular and muscular compartments. It is a supplement, not a substitute. Our caffeine-free boosters frequently combine these two approaches.

What are the dangers of L-arginine?

The question of the dangers of L-arginine deserves a precise answer rather than a reassuring statement. At dietary doses, this amino acid is consumed daily by everyone without difficulty. At supplementation doses, a few points deserve real attention.

Digestive disorders. This is the most common side effect, and it is dose-dependent. Beyond 5 to 10 g in a single dose, nausea, bloating, abdominal cramps, and diarrhea become common. The mechanism is partly osmotic: a large load of free amino acid in the intestine draws water. Splitting the dose and taking it with some food limits the problem.

Interactions with vasodilators and antihypertensive treatments. This is the most important point, and it is not theoretical. Arginine acts on the same pathway as several classes of medications: nitrates, antihypertensive treatments, PDE5 inhibitors. The addition of two vasodilatory effects can cause blood pressure to drop beyond what is desirable. If you are on any of these treatments, the question must be posed to your doctor or pharmacist before starting, not after.

Herpes. The HSV virus uses arginine for its replication, and the ratio between arginine and lysine in the diet is a factor discussed in the occurrence of outbreaks. The data is not definitive, but if you are prone to recurrent outbreaks, this is something to consider and discuss with your doctor before prolonged high-dose supplementation.

Kidney and liver pathologies. Arginine is part of the urea cycle, which the liver and kidneys ensure functions and eliminates products. In cases of kidney or liver failure, an additional load of amino acids is not trivial and requires medical advice.

Specific situations. Pregnancy and breastfeeding, post-infarction period, severe asthma, and ongoing treatments in general: caution involves seeking advice from a healthcare professional rather than relying on a label. There is nothing alarming for a healthy adult who respects the doses, but nothing that justifies ignoring these situations either. European evaluations of amino acids in dietary supplements are the responsibility of the EFSA, and French recommendations are from ANSES.

What dose and when?

For training-related use, the useful range is between 3 and 6 g, taken 45 to 60 minutes before the session — a longer delay than for citrulline, whose peak is later but pathway is more direct. AAKG forms are used in the same range.

Start with 3 g to assess your digestive tolerance before going higher. Beyond 6 g in a single dose, the discomfort-to-benefit ratio significantly deteriorates.

If you are already taking citrulline, there is no reason to add a high dose of arginine on top: both feed the same pathway, and the latter is the less effective of the two orally. Conversely, arginine combines easily with ingredients that act through other mechanisms: beta-alanine for acid buffering, electrolytes for hydration, EAAs during training.

Frequently Asked Questions

What is L-arginine?

A semi-essential amino acid: the body can produce it, but not always in sufficient quantities during growth or significant physiological stress. The "L-" prefix simply denotes the natural form, the one found in dietary proteins. As a supplement, it comes as pure powder, capsules, or in salt form such as arginine HCl and AAKG. Its most commented role in sports nutrition is to be the direct precursor of nitric oxide, the molecule that relaxes blood vessel walls and increases local blood flow.

What are the benefits of L-arginine?

First, it's important to state what doesn't exist: no health claims are authorized in Europe for arginine, as none have passed evaluation by the EFSA. What is documented pertains to physiology, not promised benefits. It is the substrate for NO-synthase, and thus for nitric oxide and vasodilation; it is a link in the urea cycle, through which nitrogen from proteins is eliminated; it serves as a precursor to endogenous creatine and polyamines involved in cell renewal. Useful to know, but insufficient to promise a specific outcome.

What effects does L-arginine have?

Honestly, very little, and this is what often leads to disappointment. The only noticeable effect is sometimes a slightly more pronounced pump during training, with doses of 3 to 6 g taken 45 to 60 minutes beforehand: veins become more visible, muscles appear fuller. The sensation is real but modest, and many cannot distinguish it from a placebo. No stimulating effect, no energy boost, no strength gain: in this regard, creatine monohydrate remains the benchmark supplement.

When should I take arginine?

45 to 60 minutes before your workout if your goal is muscle pump—a longer delay than for citrulline, allowing time for the fraction escaping the liver to reach circulation. On an empty stomach or away from a protein-rich meal is preferable: other amino acids compete for the same intestinal transporters. Outside of training, no specific time has shown particular benefit, including evening intake sometimes presented as favorable for growth hormone: protocols showing this effect used intravenous doses unrelated to a capsule.

How much arginine per day?

Between 3 and 6g per dose for training-related use. Below 3g, the intestine and liver capture almost the entire dose, and nothing measurable happens—formulas displaying 500mg per serving check a marketing box. Beyond 6g in a single dose, digestive comfort significantly deteriorates without additional benefit, as the enzyme that degrades arginine is simply more active. Start at 3g to assess your tolerance, and don't forget to account for the arginine already present in your booster.

What are the dangers of arginine?

At dietary doses, none: everyone consumes it daily. At supplementation doses, four points deserve real attention. First, digestive issues—nausea, bloating, diarrhea beyond 5 to 10 g in a single dose. Second, drug interactions, and this is the most important point: arginine acts on the same pathway as nitrates, antihypertensives, and PDE5 inhibitors, and the addition of two vasodilatory effects can cause blood pressure to drop—ask your doctor before, not after. Third, herpes: the virus uses arginine to replicate, a factor to consider in cases of recurrent outbreaks. Finally, kidney or liver failure, as arginine is part of the urea cycle. Pregnancy, breastfeeding, and ongoing treatments fall under the same precautionary principle.

Is L-arginine a vasodilator?

Indirectly. It is the substrate that NO-synthase converts into nitric oxide, which relaxes the smooth muscle of the vascular wall and increases local blood flow: it is not the arginine itself that dilates, but its raw material. Two nuances are important. The oral route is not efficient, as the intestine and liver capture most of the dose before it reaches circulation. And it is precisely this vascular action that dictates the main precaution for the product: never add it to a vasodilator or antihypertensive treatment without medical advice.

Does arginine cause weight gain?

No. A dose of 3 to 6 g provides twelve to twenty kilocalories, an amount without effect on the day's energy balance. The only weight variation sometimes observed with pump formulas comes from water retained by glycerol or creatine that accompanies them, not from arginine, and it disappears upon discontinuation.

Does arginine make you grow taller?

No, and this confusion must be cleared up directly. The idea comes from studies in the 1990s showing that a high-dose intravenous infusion of arginine causes a transient peak of growth hormone—a test used in endocrinology, not an effect reproducible with a capsule. Orally, the elevation is small, brief, and has no demonstrated consequence on height, muscle mass, or recovery. Adult height depends on genetics, overall nutrition during growth, and hormonal status: no dietary supplement modifies it. For children and adolescents, these products are not indicated, and any growth-related questions should be addressed to a doctor.

Where can I find arginine, and which food contains the most?

The densest sources are not what you might expect: pumpkin seeds, peanuts, almonds, walnuts, and sesame seeds contain proportionally more than meat. Next are turkey, chicken, pork, fish, dairy products, soy, chickpeas, and lentils. A typical diet provides several grams per day, which is largely sufficient for a healthy adult. The Ciqual database details the amino acid composition food by food.

What is the value of arginine sold in pharmacies?

It's the same amino acid, obtained through the same fermentation processes. Differences lie in the galenic form—sachets, ampoules, capsules—, the dosage per unit, and associations with other active ingredients, which often drive up the price per gram. Some presentations are also medicinal products, with their own indications and follow-up: they do not translate to self-decided training supplementation. Compare the actual amount of arginine per dose and the price per gram, rather than the distribution channel.

L-arginine or citrulline, which to choose?

Citrulline, in almost all cases where the goal is muscle pump during training. It raises blood arginine levels more than arginine itself, for the reasons explained above. Arginine still has its place in combined formulas and in AAKG form.

Can it be combined with a booster?

Yes, provided the doses are added up. Many pump formulas already contain arginine or AAKG: check the label before adding more, just as you would for citrulline. The boosters section and our selection of creatine-free pre-workouts detail how to read a nutritional label.

What forms of arginine do we offer?

Our selection covers both approaches. IO.Genix offers Kyowa quality arginine, a fermentation manufacturing benchmark, for those who want the amino acid alone and well-identified. Sinob offers the AAKG version, intended for pump formulas. Peak Performance Nutrition completes the range with liquid glycerol, which acts on cell volume through a distinct mechanism and combines well with an arginine or citrulline base.

If your goal is purely pump, the honest comparison remains with the citrulline section, which is more effective at equal doses and generally better tolerated digestively.

Discuss near Montpellier

Our store in Vendargues, about ten minutes from Montpellier, allows you to ask questions that don't belong in a product sheet, starting with questions about ongoing treatments. We prefer to suggest another product, or recommend consulting your doctor, rather than selling a supplement that isn't suitable for your situation. We also ship throughout France and Europe.

Sources

À intégrer dans une alimentation variée et équilibrée et un mode de vie sain.

Questions fréquentes — L-Arginine

Qu'est-ce que la L-arginine ?

Un acide aminé semi-essentiel : l'organisme sait le fabriquer, mais pas toujours en quantité suffisante lors de la croissance ou d'un stress physiologique important. Le préfixe « L- » désigne simplement la forme naturelle, celle que l'on trouve dans les protéines alimentaires. En supplément, elle se présente en poudre pure, en gélules, ou sous forme salifiée comme l'arginine HCl et l'AAKG. Son rôle le plus commenté en nutrition sportive est d'être le précurseur direct de l'oxyde nitrique, la molécule qui relâche la paroi des vaisseaux et augmente le débit sanguin local.

Quels sont les bienfaits de la L-arginine ?

Le cadre d'abord : aucune allégation de santé n'est autorisée en Europe pour l'arginine, l'EFSA n'en ayant validé aucune. Ce qui est documenté relève de la physiologie : elle est le substrat de la NO-synthase, donc de l'oxyde nitrique et de la vasodilatation ; elle est un maillon du cycle de l'urée, par lequel l'azote issu des protéines est éliminé ; elle sert de précurseur à la créatine endogène et aux polyamines du renouvellement cellulaire.

Quels effets ressent-on avec la L-arginine ?

Le ressenti possible est une congestion un peu plus marquée à l'entraînement, sur des doses de 3 à 6 g prises 45 à 60 minutes avant : les veines ressortent, le muscle paraît plus plein. L'arginine n'est pas un stimulant : pas de coup de fouet. Pour la force maximale, c'est la créatine monohydrate qui est le complément de référence.

Quand prendre de l'arginine ?

45 à 60 minutes avant la séance si votre objectif est la congestion. À jeun ou à distance d'un repas riche en protéines de préférence : les autres acides aminés entrent en compétition pour les mêmes transporteurs intestinaux. En dehors de l'entraînement, aucun moment n'a démontré d'intérêt particulier, y compris la prise du soir parfois présentée comme favorable à l'hormone de croissance : les protocoles qui montraient cet effet utilisaient des doses intraveineuses sans rapport avec une gélule.

Quelle quantité d'arginine par jour ?

Entre 3 et 6 g par prise pour un usage lié à l'entraînement. En dessous de 3 g, l'intestin et le foie captent l'essentiel de la dose : c'est le chiffre à vérifier sur une étiquette. Au-delà de 6 g en une fois, le confort digestif se dégrade sans bénéfice supplémentaire, l'enzyme qui dégrade l'arginine étant davantage sollicitée. Commencez à 3 g pour évaluer votre tolérance, et comptez l'arginine déjà présente dans votre booster.

Quels sont les points de vigilance de l'arginine ?

Aux doses alimentaires, aucun : tout le monde en consomme quotidiennement. Aux doses de supplémentation, quatre points méritent une attention réelle. Les troubles digestifs d'abord — nausées, ballonnements, diarrhées au-delà de 5 à 10 g en une prise. Les interactions médicamenteuses ensuite, et c'est le point le plus important : l'arginine agit sur la même voie que les dérivés nitrés, les antihypertenseurs et les inhibiteurs de la PDE5, et l'addition de deux effets vasodilatateurs peut faire chuter la tension — posez la question à votre médecin avant de commencer. L'herpès ensuite : le virus utilise l'arginine pour se répliquer, un élément à évoquer en cas de poussées récurrentes. L'insuffisance rénale ou hépatique enfin, l'arginine s'inscrivant dans le cycle de l'urée. Grossesse, allaitement et traitements en cours relèvent du même principe de précaution.

La L-arginine est-elle un vasodilatateur ?

Indirectement. Elle est le substrat que la NO-synthase transforme en oxyde nitrique, lequel relâche la musculature lisse de la paroi vasculaire et augmente le débit sanguin local : c'est donc sa matière première. Deux nuances comptent. Par voie orale, l'intestin et le foie captent une grande partie de la dose, d'où la fourchette de 3 à 6 g. Et c'est précisément cette action vasculaire qui impose la principale précaution du produit : ne jamais l'ajouter à un traitement vasodilatateur ou antihypertenseur sans avis médical.

Est-ce que l'arginine fait grossir ?

Non. Une dose de 3 à 6 g apporte une douzaine à une vingtaine de kilocalories, une quantité sans effet sur le bilan énergétique de la journée. La seule variation de poids parfois observée avec les formules de congestion vient de l'eau retenue par le glycérol ou la créatine qui les accompagnent, et elle disparaît à l'arrêt.

Est-ce que l'arginine fait grandir ?

Non. L'idée vient de travaux des années 1990 montrant qu'une perfusion intraveineuse d'arginine à forte dose provoque un pic transitoire d'hormone de croissance — un test utilisé en endocrinologie, pas un effet reproductible avec une gélule. Par voie orale, l'élévation est faible et brève. La taille adulte dépend de la génétique, de la nutrition globale pendant la croissance et du statut hormonal. Chez l'enfant et l'adolescent, ces produits ne sont pas indiqués, et toute question de croissance relève du médecin.

Où trouver de l'arginine, et quel aliment en contient le plus ?

Les sources les plus denses ne sont pas celles qu'on imagine : les graines de courge, les cacahuètes, les amandes, les noix et les graines de sésame en contiennent proportionnellement plus que la viande. Viennent ensuite la dinde, le poulet, le porc, les poissons, les produits laitiers, le soja, les pois chiches et les lentilles. Une alimentation ordinaire en apporte plusieurs grammes par jour. La base Ciqual détaille la composition en acides aminés aliment par aliment.

Quelle forme d'arginine choisir ?

Toutes les présentations apportent le même acide aminé, obtenu par fermentation. Les différences portent sur la forme — poudre pure, gélules, arginine HCl, AAKG —, sur la quantité réelle d'arginine par prise et sur les associations avec d'autres actifs. C'est donc la dose par prise, lue sur le tableau nutritionnel, qui permet de comparer deux produits.

L-arginine ou citrulline, laquelle choisir ?

La citrulline, dans la quasi-totalité des cas où l'objectif est la congestion à l'entraînement. Elle élève davantage l'arginine sanguine que l'arginine elle-même, pour les raisons expliquées plus haut. L'arginine garde sa place dans les formules combinées et sous forme d'AAKG.

Peut-on l'associer à un booster ?

Oui, à condition d'additionner les doses. Beaucoup de formules pump contiennent déjà de l'arginine ou de l'AAKG : vérifiez l'étiquette avant d'en ajouter, comme vous le feriez pour la citrulline. Le rayon boosters et notre sélection pre-workout sans créatine détaillent la lecture d'un tableau nutritionnel.