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What is IO Genix Glycine?
IO Genix Glycine is a pure L-glycine powder. Half a level scoop provides 3 g of glycine, and the manufacturer sets the daily intake at 6 g split into two servings. There is nothing else in the tub: no flavouring, no sweetener, no bulking agent.
One point needs clearing up first, because it causes constant confusion in search engines: the glycine we are talking about here has nothing to do with the climbing plant of the same name. It is an amino acid, the smallest and simplest of the twenty that make up the body's proteins. It is described as non-essential because the body can produce it itself, from serine.
Glycine is particularly abundant in one specific tissue: collagen is roughly one third glycine, which makes it the most heavily represented amino acid in skin, tendons and cartilage. In dietary terms, it is found mainly in the cuts that are rich in connective tissue — skin, bones, cartilage — which is precisely what modern eating habits have stopped including. The rest of the Spanish range is in our IO Genix aisle, and the full category in our L-glycine aisle.
What does a serving of Glycine contain?
| Values | Per 3 g serving | Per 6 g (daily intake) |
|---|---|---|
| L-glycine | 3 g (100% pure) | 6 g |
| Energy | 12 kcal | 24 kcal |
| Protein | 3 g | 6 g |
| Carbohydrate | 0 g | 0 g |
| Fat | 0 g | 0 g |
| Nutrient reference value | Not established for glycine | |
100% glycine is literally all this tub contains, and that is the strongest argument for this format. On an aisle where fifteen-ingredient formulas are the norm, a product whose ingredient list runs to three words lets you know exactly what you are swallowing and adjust the dose to the gram.
Two features of the product are worth knowing before you buy. The first: the glycine is obtained by plant fermentation, which makes this powder suitable for vegetarian and vegan diets — an exception on an aisle largely dominated by gelatine. The second: it is declared gluten-free by the manufacturer, although traces from the production facility remain possible.
One regulatory point needs to be clear: no health claim is authorised in Europe for glycine. Not for sleep, not for recovery, not for skin, not for joints. It is an amino acid abundantly present in collagen — that is a fact of biochemistry, not a promise — and the European Union has approved no dossier for oral supplementation. We describe the molecule, its place in the body and how to use it, without announcing any result.
Data missing from the manufacturer's file: the net weight of the tub, and therefore the number of servings, are not disclosed. We will not infer them. The net content is shown on the packaging you receive.
Ingredients list
Pure L-glycine (100%). Produced by plant fermentation. No additives, no colourings, no preservatives.
May contain traces of GLUTEN (wheat and oats), NUTS, PEANUTS, EGGS, MILK, FISH and SOYA.
How do you take Glycine?
Dose: 3 g, or roughly half a 5 ml spoon. Liquid: 200 to 250 ml of water, fruit juice or plant-based drink. Timing: in the morning on waking, and 30 minutes before bed. Frequency: two servings a day, 6 g in total. Duration: daily use is possible with no time limit, provided the doses are respected.
The most useful quirk of this powder is its taste: glycine is naturally sweet. That is not a turn of phrase — its name comes from the Greek glykys, meaning sweet. In practice, it dissolves into a coffee, a tea or a herbal infusion and sweetens them slightly, without adding sugar in the nutritional sense. It is a simple way of fitting both daily servings in without thinking about them.
It dissolves very well in water, with no lumps, which is not true of every powdered amino acid. It also goes into a smoothie, a protein shake or a yoghurt without any difficulty.
The evening serving, thirty minutes before bed, is the one the manufacturer recommends. It is the easier of the two to keep up over time for a practical reason: it is a fixed point in the day, unlike waking up, which varies.
Do not exceed 6 g per day. This product can be taken continuously, with no imposed cycle or break, which sets it apart from most references on this aisle. It combines without overlap with magnesium, collagen or taurine, and it often turns up in the same baskets as melatonin.
Who is glycine for, and who is it not for?
It is of interest first of all to those whose diet contains little connective tissue — which today means more or less everyone, since consumption of bone broth, skin and cartilage has fallen away very sharply. It also suits those looking for a simple, unflavoured active ingredient to slot into an already busy routine.
Its composition makes it one of the few products in the range suitable for vegans, since it is obtained by plant fermentation and there is no capsule or animal-derived shell involved. That is a genuine argument on an aisle where the question comes up with every product.
One contraindication deserves particular attention, and it is an unusual one. The manufacturer states that this product should not be used by anyone under treatment for mental health disorders, specifying that it could reduce the effectiveness of that treatment. This is not a generic form of words: it targets a specific situation, and if it applies to you, the question goes to your doctor or pharmacist before any purchase — never after.
The product is also not recommended for pregnant or breastfeeding women and must be kept out of the reach of children. It may contain traces of gluten, nuts, peanuts, eggs, milk, fish and soya.
What not to expect from it: this is not a sleeping pill, not an anxiolytic and not a performance product. You will not feel anything spectacular, and an amino acid that produced a clear effect within the hour would in fact be cause for concern. Nor is it a protein: 6 g a day replaces no shake, and a single isolated amino acid does not build muscle.
Glycine or collagen — which should you choose?
The question is more relevant than it looks, since glycine accounts for roughly one third of collagen.
Powdered collagen provides peptides, that is, protein fragments containing glycine but also proline and hydroxyproline. It is taken at much higher doses, typically 10 g a day, and costs considerably more per gram. Like glycine, it has no health claim authorised in Europe for this use. Its marine and bovine versions are not suitable for vegans.
Glycine on its own is the simplest option, the cheapest, and the only one compatible with a vegan diet. You get one specific amino acid, at a known dose, without the other components of collagen. It is the right choice if that particular molecule is what interests you, and if you want to set your own intake.
For end-of-day routines, this aisle offers other approaches unrelated to this one: magnesium, which does have authorised claims and contributes in particular to the reduction of tiredness and fatigue, or ZMA formulas. These follow different logics, and it is better to try one at a time.
Frequently asked questions
Is this the same thing as the wisteria plant?
No, no connection at all. The climbing plant called glycine in French is an ornamental plant, and some of its parts are toxic. The product sold here is an amino acid, L-glycine, one of the twenty building blocks of the body's proteins. The confusion comes purely from the shared name.
How much per day?
6 g in total, in two 3 g servings: one in the morning, one thirty minutes before bed. A 3 g dose corresponds to roughly half a 5 ml spoon. Do not exceed the daily dose stated by the manufacturer.
Does glycine have a taste?
Yes, and that is its strong point: it is naturally sweet, its name coming from the Greek for “sweet”. It can therefore be used to lightly sweeten a coffee, a tea or a herbal infusion, without adding sugar in the nutritional sense or any notable calories.
Is it suitable for vegans?
Yes. The glycine here is obtained by plant fermentation, the powder involves no animal-derived shell, and the manufacturer declares it suitable for vegetarian and vegan diets. That is a welcome exception in a range largely dominated by gelatine.
Can it be taken continuously?
The manufacturer says so: daily use is possible with no time limit, provided the recommended doses are respected. It is one of the few products on this aisle that imposes no cycle, no break and no fixed course.
Does it interact with any medication?
The manufacturer explicitly asks that this product not be used by anyone under treatment for mental health disorders, stating that it could reduce the effectiveness of that treatment. If this applies to you, the question is one for your doctor. For any other medication, seeking the opinion of a healthcare professional remains the right course.
Can it be mixed with a protein?
Yes, easily and with no known interaction. It dissolves well and its slightly sweet taste goes unnoticed in a flavoured shake. Bear in mind, though, that 3 g of glycine does not add meaningfully to your protein intake: these are two different uses.
Where can you buy IO Genix Glycine?
The powder can be ordered from this page, and we ship throughout France and Europe. At the Vendargues shop, about ten minutes from Montpellier, this is a product we often sell to vegan customers who came in looking for collagen and left with something else: when a dietary constraint closes one door, you may as well open another rather than sell at any cost. The rest of the aisle can be browsed in our sports nutrition section.
Qu'est-ce que la Glycine en poudre d'OstroVit ?
C'est de la glycine pure en poudre : la liste des ingrédients tient en un mot. Pas d'arôme, pas d'édulcorant, pas d'agent d'écoulement, rien que l'acide aminé.
Le sachet fait 200 g, et la poudre se dose à la mesurette. C'est la fiche de celui qui veut la matière première et rien autour. Le reste de la gamme se parcourt dans le rayon OstroVit.
Ce qu'il y a dans la Glycine en poudre
Un seul chiffre compte, et c'est le bon : 3 000 mg de glycine dans la portion de 3 g. Autrement dit, 100 % de glycine et aucun excipient — pas d'agent de charge, pas d'antiagglomérant, pas de colorant.
La glycine a un goût légèrement sucré, ce qui explique qu'OstroVit n'ajoute ni arôme ni édulcorant : la poudre passe seule dans un verre d'eau.
La glycine est le plus petit des acides aminés et le plus abondant du collagène, dont elle représente environ un résidu sur trois. Elle entre aussi dans la fabrication du glutathion et de la créatine, et joue le rôle de neurotransmetteur inhibiteur dans le système nerveux central. L'organisme la synthétise lui-même, ce qui la classe parmi les acides aminés non essentiels.
À qui s'adresse la Glycine en poudre ?
À celui qui veut choisir sa quantité au gramme près plutôt que de suivre un nombre de gélules. La poudre se dose comme on veut, c'est tout son intérêt.
C'est aussi la fiche de qui mange peu de tissu conjonctif : pas de bouillon d'os, pas de couennes, pas de gélatine. L'apport en glycine suit l'assiette, et l'assiette moderne a perdu ces morceaux.
Enfin, c'est le choix de celui qui refuse les excipients. Un mot sur l'étiquette, c'est le minimum possible sur un complément en poudre.
Questions fréquentes
La glycine, qu'est-ce que c'est ?
C'est le plus petit des acides aminés : un seul atome de carbone sur la chaîne latérale. C'est aussi le plus abondant du collagène, où elle occupe environ un résidu sur trois. L'organisme sait la fabriquer.
Pourquoi se supplémenter en glycine ?
Parce que l'apport alimentaire suit le tissu conjonctif, et que le tissu conjonctif a quitté nos assiettes. Bouillon d'os, couennes, pieds et jarrets : les morceaux riches en glycine sont ceux qu'on ne cuisine plus.
Pourquoi la glycine est-elle un acide aminé ?
Parce qu'elle porte les deux fonctions qui définissent la famille : un groupe amine et un groupe carboxyle sur le même carbone. C'est le modèle le plus simple de la série, et le seul qui n'ait ni forme droite ni forme gauche.
Quelle est la formule de la glycine ?
C2H5NO2, soit un carbone portant un groupe amine et un groupe acide carboxylique, avec deux hydrogènes pour toute chaîne latérale. Son autre nom est acide aminoacétique.
Où trouve-t-on de la glycine dans les aliments ?
Dans tout ce qui contient du tissu conjonctif : bouillon d'os, couennes, pieds et jarrets, peau de volaille, gélatine. Les filets maigres en apportent peu.
Glycine et sommeil : qu'en est-il ?
La glycine est un neurotransmetteur inhibiteur du système nerveux central, aux côtés du GABA. C'est ce rôle physiologique qui explique pourquoi la question revient si souvent ; l'étiquette de ce sachet, elle, n'annonce rien sur ce terrain.
Est-ce que la glycine est toxique ?
C'est un acide aminé présent dans le corps humain et dans l'alimentation courante, pas une molécule de synthèse exotique. Le corps en fabrique lui-même et en trouve dans la viande, la gélatine et les bouillons.
Où acheter la Glycine en poudre d'OstroVit ?
Le sachet de 200 g se commande depuis cette page et nous expédions partout en France et en Europe. Notre magasin se trouve à Vendargues, à une dizaine de minutes de Montpellier, et la Glycine en poudre y est en rayon.
Le reste de la marque se parcourt dans la collection OstroVit.
Qu'est-ce que la Glycine 3000 mg d'OstroVit ?
C'est de la glycine en gélules : 3 000 mg dans la dose de quatre gélules, soit 750 mg par gélule. Le flacon en compte 120, pour 30 doses.
C'est la fiche de celui qui veut cet acide aminé sans poudre à peser ni verre à remuer. Le reste de la gamme se parcourt dans le rayon OstroVit.
Ce qu'il y a dans la Glycine 3000 mg
Deux chiffres résument l'étiquette : 3 000 mg de glycine dans la dose, et 120 gélules dans le flacon, pour 108 g net.
Autant le dire franchement : la liste des ingrédients ne s'arrête pas à la glycine. On y trouve aussi de l'hydroxypropylméthylcellulose, déclarée comme agent de charge, et de la L-leucine, qui sert d'agent de glisse à la fabrication. Le tableau nutritionnel ne déclare que les 3 000 mg de glycine ; la leucine n'y figure pas avec un dosage.
La glycine est le plus petit des acides aminés et l'un des plus abondants du collagène, où elle occupe environ un résidu sur trois. Elle entre aussi dans la fabrication du glutathion et de la créatine, et joue le rôle de neurotransmetteur inhibiteur dans le système nerveux central. L'organisme la synthétise lui-même, ce qui la classe parmi les acides aminés non essentiels.
À qui s'adresse la Glycine 3000 mg ?
À celui qui mange peu de tissu conjonctif : pas de bouillon d'os, pas de couennes, pas de gélatine. L'apport alimentaire en glycine suit l'assiette, et l'assiette moderne a perdu ces morceaux.
C'est aussi le format de qui voyage ou travaille en déplacement. Un flacon se glisse dans un sac là où un sachet de poudre et sa mesurette ne suivent pas.
Enfin, c'est la fiche de celui qui lit les étiquettes. Trois lignes d'ingrédients, un dosage écrit noir sur blanc : il reste peu de place pour l'approximation.
Questions fréquentes
Qu'est-ce que la glycine ?
C'est le plus petit des acides aminés : un seul atome de carbone sur la chaîne latérale. C'est aussi l'un des plus abondants du collagène, où elle occupe environ un résidu sur trois. L'organisme sait la fabriquer.
Pourquoi prendre de la glycine ?
Parce que c'est une brique de structure et un neurotransmetteur à la fois. Elle entre dans la fabrication du collagène, du glutathion et de la créatine, et l'alimentation moderne, pauvre en tissu conjonctif, en apporte moins qu'autrefois.
Pourquoi la glycine est-elle un acide aminé ?
Parce qu'elle porte les deux fonctions qui définissent la famille : un groupe amine et un groupe carboxyle sur le même carbone. C'est le modèle le plus simple de la série, et le seul qui n'ait pas de forme droite ou gauche.
Quelle est la formule de la glycine ?
C2H5NO2, soit un carbone porteur d'un groupe amine et d'un groupe acide carboxylique, et deux atomes d'hydrogène pour toute chaîne latérale. Son autre nom est acide aminoacétique.
Où trouve-t-on de la glycine dans les aliments ?
Dans tout ce qui contient du tissu conjonctif : bouillon d'os, couennes, pieds et jarrets, peau de volaille, gélatine. Les filets maigres, eux, en apportent peu.
Glycine et sommeil : qu'en est-il ?
La glycine est un neurotransmetteur inhibiteur du système nerveux central, aux côtés du GABA. C'est ce rôle physiologique qui explique pourquoi la question revient si souvent ; l'étiquette de ce flacon, elle, n'annonce rien sur ce terrain.
Est-ce que la glycine est toxique ?
C'est un acide aminé présent dans le corps humain et dans l'alimentation courante, pas une molécule de synthèse exotique. Le corps en fabrique lui-même et en trouve dans la viande, la gélatine et les bouillons.
Où acheter la Glycine 3000 mg d'OstroVit ?
Le flacon de 120 gélules se commande depuis cette page et nous expédions partout en France et en Europe. Notre magasin se trouve à Vendargues, à une dizaine de minutes de Montpellier, et la Glycine y est en rayon.
Le reste de la marque se parcourt dans la collection OstroVit.
Qu'est-ce que la Glycine en Poudre de NOW Foods ?
C'est de la glycine pure en poudre, en pot de 454 g. La liste d'ingrédients tient en un mot : glycine. Aucun excipient, aucun agent d'écoulement, aucun arôme.
Une dose de 3 g, soit environ trois quarts de cuillère à café rase, apporte 3 000 mg de glycine. Le pot en contient environ 151.
Ce qui distingue ce produit
Rien d'autre que l'actif. Sur l'étiquette, la rubrique « autres ingrédients » porte la mention « aucun ». C'est rare, même sur les poudres.
Un dosage libre. La cuillère permet d'ajuster la dose, ce que la gélule ne permet pas.
Le goût
La glycine a un goût franchement sucré — c'est d'ailleurs ce que signifie son nom. Elle se dissout sans difficulté dans l'eau ou le jus. Ce goût ne dérange pas tout le monde, mais il vaut mieux le savoir avant d'ouvrir le pot. Si vous préférez l'éviter, les gélules de glycine 1000 mg existent.
Questions fréquentes
Y a-t-il des additifs ?
Non. L'étiquette indique « aucun » à la rubrique des autres ingrédients : le pot ne contient que de la glycine.
Quel goût ?
Nettement sucré. La glycine se dissout facilement dans l'eau ou un jus.
Le produit convient-il aux végétaliens ?
Oui, la glycine est obtenue par synthèse et non extraite de collagène animal.
Contient-il des allergènes ?
Le fabricant indique que le produit n'est pas fabriqué avec du blé, du gluten, du soja, du lait, de l'œuf, du poisson, des crustacés, des fruits à coque ni du sésame. L'atelier traite par ailleurs d'autres ingrédients contenant ces allergènes.
Qu'est-ce que la Glycine 1000 mg de NOW Foods ?
C'est de la glycine sous forme libre, en gélules végétales dosées à 1 000 mg. La glycine est le plus petit des acides aminés : une seule molécule de carbone sur sa chaîne latérale. C'est aussi le plus abondant dans le collagène, dont elle représente environ un acide aminé sur trois.
L'organisme sait la fabriquer, et on la trouve dans les aliments riches en tissu conjonctif : bouillons d'os, peau, cartilage, gélatine.
Ce qui distingue ce produit
Sous forme libre. La glycine n'est liée à rien : ce n'est ni un sel ni un complexe. Le milligramme affiché est de la glycine.
Une formule sans rien d'inutile. La glycine, l'enveloppe végétale, un peu d'hydroxypropylcellulose, d'acide stéarique végétal et de dioxyde de silicium.
La gélule plutôt que la poudre. La glycine a un goût sucré prononcé que tout le monde n'apprécie pas. La gélule l'évite.
Questions fréquentes
Qu'est-ce que la « forme libre » ?
Cela signifie que l'acide aminé n'est pas lié à une autre molécule : il n'est ni salifié ni intégré à un peptide. Les 1 000 mg annoncés sont bien 1 000 mg de glycine.
Le produit convient-il aux végétaliens ?
Oui. L'enveloppe est en hypromellose, d'origine végétale, et la glycine est obtenue par synthèse, pas extraite de collagène animal.
Contient-il des allergènes ?
Le fabricant indique que le produit n'est pas fabriqué avec du blé, du gluten, du soja, du lait, de l'œuf, du poisson, des crustacés, des fruits à coque ni du sésame. L'atelier traite par ailleurs d'autres ingrédients contenant ces allergènes.
Quelle différence avec la poudre ?
Le prix au gramme et la souplesse de dosage, au prix du goût et de la préparation.
What is L-Glycine, and why are we not talking about the plant here?
The word "glycine" refers to several unrelated things. The most well-known is a climbing vine with purple clusters, which can be pruned and propagated by cuttings — this is not our subject, and if it is yours, a garden center will serve you better than we will. This section only deals with the amino acid glycine, sold as a white crystalline powder, sometimes labeled as "crystallized glycine" or by its biological form, L-Glycine.
An amino acid is a basic building block of proteins. Twenty of them make up human proteins, and glycine is the smallest of them all: its side chain is reduced to a single hydrogen atom. Its chemical formula is C₂H₅NO₂, and its molar mass is approximately 75 g/mol. This small size explains the particular place it occupies in certain proteins, and the fact that it is the only one of the twenty that does not exist in two mirror forms: strictly speaking, referring to "L-Glycine" is a commercial pleonasm, inherited from the nomenclature of other amino acids.
Glycine is a non-essential amino acid. This does not mean that it is optional, but that the body can produce it, mainly from serine. It is also abundant in food, particularly in connective tissues: skin, cartilage, tendons, bones to gnaw on, long-simmered broths, gelatin.
A final distinctive, immediately perceptible feature: glycine has a sweet taste. Its name comes from the Greek glykys, which means sweet. It is also used as a food additive under the code E640. It is the only common amino acid that can be consumed without making a face, which changes daily practice — we will come back to this below.
What is the role of glycine in the body?
Collagen. This is its most spectacular role in terms of quantity. Collagen is a triple-helix protein whose winding is only possible if a tiny amino acid occupies one position out of three, at the heart of the helix, where no other side chain would fit. This amino acid is glycine: it represents approximately one residue out of three in collagen, a proportion unmatched in other body proteins.
Creatine. The body synthesizes it from three amino acids: arginine, methionine, and glycine. A portion of the available glycine therefore goes into this pathway. This does not make a glycine supplement a substitute for creatine monohydrate, which remains by far the most direct way to increase muscle reserves.
Glutathione. This tripeptide is formed from glutamate, cysteine, and glycine. Cysteine is usually the limiting factor, which explains the interest in N-acetylcysteine, but glycine is indeed one of its three constituents.
Other pathways. Glycine is involved in the synthesis of heme, the part of hemoglobin that carries iron, and in the synthesis of bile salts.
The nervous system. This is the least known aspect to the general public: glycine is also an inhibitory neurotransmitter, acting on its own receptors, mainly in the spinal cord and brainstem. It also plays a co-agonist role on glutamate's NMDA receptors. This dual role explains why it is found in evening formulas, alongside GABA or melatonin.
An essential clarification: no health claims are authorized for glycine at the European level. The functions above are biochemical facts, not promises of effect. Describing the role of a molecule in the body and claiming that ingesting it produces a benefit are two different things, and we will not confuse the two.
Glycine or collagen: which to choose?
A hydrolyzed collagen provides peptides derived from collagen: glycine in large quantities, but also proline, hydroxyproline, and the other amino acids of the protein, in natural proportions. A pure glycine provides only glycine. The first is a mixture, the second a unique compound — that's the whole difference.
Three practical consequences. The price per gram: pure glycine is significantly cheaper, and if your only goal is a glycine intake, it is the economical route. The taste: collagen is neutral to slightly meaty, glycine distinctly sweet. The origin: collagen is animal, bovine, porcine, or marine, while supplemental glycine is obtained by synthesis or fermentation, which makes it compatible with a vegan diet — check the label for this information.
What we will not say is that one "replaces" the other for skin or joints. No claims exist for either glycine or collagen in this regard. If your concern is joint-related, glucosamine is another option; if your concern is overall protein intake, it is addressed with proteins.
What dose of glycine, when, and in what form?
Glycine is most often sold as a powder, which is logical for a molecule taken in grams rather than milligrams. It dissolves easily in cold water and its sweet taste makes it pleasant as is; it can also be added to a sugar-free drink, yogurt, or an evening infusion. Capsules exist, but many are needed to reach usual quantities.
Doses suggested by manufacturers generally range from 1 to 5 g per serving, with the 3 g portion being the most common. In the absence of an authorized claim, there is no official reference dose: what you read on a container is a suggestion, not a validated threshold. Start at the lower end of the range.
The most common time is in the evening, about thirty minutes before bedtime — this is the dominant use in compound formulas. Nothing dictates this slot if you take it for its amino acid contribution: it is then distributed indifferently throughout the day. At very high doses, the main reported inconvenience is digestive, and it is managed by fractioning the intake.
A usage tip, since we're talking about taste: glycine can be used to sweeten a bitter preparation, coffee, a shaker of essential amino acids, whose bitterness discourages many people. This is not a health property, it is a taste property, and it is very real.
Does glycine pose any danger?
It is an amino acid present in large quantities in common foods and in our own tissues, which places the subject far from risky molecules. At usual doses, tolerance is good, and reported adverse effects are primarily digestive: bloating, loose stools, gastric discomfort, especially beyond a few grams in a single dose. Slight drowsiness is sometimes mentioned in the evening.
Situations that require prior medical advice are classic: pregnancy and breastfeeding, due to lack of data; children and adolescents, this section being aimed at adults; renal or hepatic insufficiency, any additional nitrogen intake must be discussed; ongoing treatment affecting the central nervous system, as glycine has neurotransmitter activity; and any known metabolic disease concerning amino acid metabolism.
Finally, a remark that applies to all pages in this section: if your sleep is chronically degraded, no supplement will replace a doctor's diagnosis.
Frequently Asked Questions
What is the chemical formula for glycine?
C₂H₅NO₂, also written as NH₂-CH₂-COOH to show its structure: an amine group, a central carbon, a carboxylic acid group, and a single hydrogen atom as its side chain. Molar mass of approximately 75 g/mol.
Glycine: what is the definition?
In nutrition, glycine is the smallest of the twenty proteinogenic amino acids, non-essential because the body can synthesize it, with a sweet taste, and very abundant in collagen. The same word also refers to an ornamental climbing plant, with no connection whatsoever.
What is an amino acid, and is glycine an essential one?
An amino acid is a molecule combining an amine group and an acid group, which serves as a building block for proteins. An amino acid is called "essential" if the body cannot produce it and it must come from food — there are nine in adults, and glycine is not one of them. EAAs specifically refer to these essential amino acids.
What are the benefits of glycine?
The honest answer is twofold, and both are true at the same time. Biochemically, glycine is indispensable: one in three residues of collagen, one of the three constituents of glutathione, one of the three precursors of creatine, an inhibitory neurotransmitter of the nervous system. From a regulatory standpoint, no health claims are authorized in Europe for glycine: no one is allowed to announce that ingesting it produces such or such a benefit, and we will not do so any more than others. A seller who only gives you the first half of this answer is selling you a promise, not a product.
What is the composition of glycine powder?
Good glycine contains only one thing: glycine, declared at 99% or more, without flavor, without sweetener, without coloring, without anti-caking agent. It is one of the few products in the store whose ingredient list is a single word. If you read several, ask yourself what they are doing there — the powder is already naturally sweet, it doesn't need anything.
When should I take glycine?
In the evening, half an hour before bedtime, in the most common usage. For a simple amino acid intake, the timing is of little importance. In both cases, regularity matters more than the specific time.
Which glycine should I choose?
Three criteria are sufficient. The stated purity, and the presence of a certificate of analysis if the manufacturer publishes it. The form: powder, because a 3g dose would require six 500mg capsules. And the fineness of the grind, which determines dissolution: overly coarse glycine leaves a deposit at the bottom of the glass. The rest — synthetic or fermentation origin, presence of a measuring scoop — falls under comfort and your dietary constraints.
Is glycine toxic?
No, not the amino acid: it is a normal component of our proteins and diet, which the body produces itself every day, and the discomfort of an excess remains digestive. Be careful, however, with the homonym: the climbing plant, on the other hand, is toxic — its seeds and pods cause serious digestive problems if ingested, especially in children. This is one more reason not to confuse the two, and a case where a call to a poison control center is justified.
Is glycine beneficial for the skin?
What can be stated is limited to biochemistry: glycine is the most frequent residue of collagen, which is the major structural protein of the dermis. No European claim authorizes us to deduce an effect on the skin, and we will not do so. The collagen section addresses the topic in more detail.
Can it be combined with other supplements?
Yes, with no documented interactions at usual doses with common micronutrients. It is frequently found alongside magnesium — magnesium bisglycinate is nothing more than magnesium chelated with two glycine molecules — melatonin or ZMA. Simply add up the contributions.
What is the price of glycine?
It is one of the cheapest amino acids in the department, and the right benchmark is not the price of the jar but the price per gram. A 500g package taken at 3g represents approximately 165 servings: on a daily basis, the difference between two brands often comes down to a few cents. For equivalent purity, paying significantly more for glycine has no technical justification.
Where to buy glycine powder?
Here, or in our store. The point to check is the stated purity and the absence of superfluous additives: good glycine is a white powder, without added flavor or sweetener, as it is already sweet.
Glycine and sleep: what can be said?
That glycine is an inhibitory neurotransmitter, that evening formulas often contain it, and that no health claim authorizes advertising an effect on sleep. The only active ingredient in this category that has an official claim for falling asleep is melatonin, at 1 mg per dose.
What selection do we offer?
For such a simple compound, there aren't thirty criteria: glycine is judged by its purity, the fineness of its powder — which determines dissolution — and the honesty of its labeling. IO.Genix offers pure glycine powder, with no additives. Alongside it, our amino acid section includes glutamine and taurine, and our complete guide to sports nutrition explains how they work together.
An opinion in store near Montpellier?
In Vendargues, about ten minutes from Montpellier, our store can answer in two minutes a question that often lingers online: the real dose and how to take it. A three-gram powder is not measured with a tablespoon, and seeing the measuring scoop helps. We also ship throughout France and Europe. We will explain what glycine does in the body; we will not promise what no claim allows us to promise.
Sources: Ciqual for the amino acid composition of foods; EFSA for the register of authorized health claims, where glycine is not listed; ANSES for benchmarks related to food supplements.
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What is L-Glycine, and why are we not talking about the plant here?
The word "glycine" refers to several unrelated things. The most well-known is a climbing vine with purple clusters, which can be pruned and propagated by cuttings — this is not our subject, and if it is yours, a garden center will serve you better than we will. This section only deals with the amino acid glycine, sold as a white crystalline powder, sometimes labeled as "crystallized glycine" or by its biological form, L-Glycine.
An amino acid is a basic building block of proteins. Twenty of them make up human proteins, and glycine is the smallest of them all: its side chain is reduced to a single hydrogen atom. Its chemical formula is C₂H₅NO₂, and its molar mass is approximately 75 g/mol. This small size explains the particular place it occupies in certain proteins, and the fact that it is the only one of the twenty that does not exist in two mirror forms: strictly speaking, referring to "L-Glycine" is a commercial pleonasm, inherited from the nomenclature of other amino acids.
Glycine is a non-essential amino acid. This does not mean that it is optional, but that the body can produce it, mainly from serine. It is also abundant in food, particularly in connective tissues: skin, cartilage, tendons, bones to gnaw on, long-simmered broths, gelatin.
A final distinctive, immediately perceptible feature: glycine has a sweet taste. Its name comes from the Greek glykys, which means sweet. It is also used as a food additive under the code E640. It is the only common amino acid that can be consumed without making a face, which changes daily practice — we will come back to this below.
What is the role of glycine in the body?
Collagen. This is its most spectacular role in terms of quantity. Collagen is a triple-helix protein whose winding is only possible if a tiny amino acid occupies one position out of three, at the heart of the helix, where no other side chain would fit. This amino acid is glycine: it represents approximately one residue out of three in collagen, a proportion unmatched in other body proteins.
Creatine. The body synthesizes it from three amino acids: arginine, methionine, and glycine. A portion of the available glycine therefore goes into this pathway. This does not make a glycine supplement a substitute for creatine monohydrate, which remains by far the most direct way to increase muscle reserves.
Glutathione. This tripeptide is formed from glutamate, cysteine, and glycine. Cysteine is usually the limiting factor, which explains the interest in N-acetylcysteine, but glycine is indeed one of its three constituents.
Other pathways. Glycine is involved in the synthesis of heme, the part of hemoglobin that carries iron, and in the synthesis of bile salts.
The nervous system. This is the least known aspect to the general public: glycine is also an inhibitory neurotransmitter, acting on its own receptors, mainly in the spinal cord and brainstem. It also plays a co-agonist role on glutamate's NMDA receptors. This dual role explains why it is found in evening formulas, alongside GABA or melatonin.
An essential clarification: no health claims are authorized for glycine at the European level. The functions above are biochemical facts, not promises of effect. Describing the role of a molecule in the body and claiming that ingesting it produces a benefit are two different things, and we will not confuse the two.
Glycine or collagen: which to choose?
A hydrolyzed collagen provides peptides derived from collagen: glycine in large quantities, but also proline, hydroxyproline, and the other amino acids of the protein, in natural proportions. A pure glycine provides only glycine. The first is a mixture, the second a unique compound — that's the whole difference.
Three practical consequences. The price per gram: pure glycine is significantly cheaper, and if your only goal is a glycine intake, it is the economical route. The taste: collagen is neutral to slightly meaty, glycine distinctly sweet. The origin: collagen is animal, bovine, porcine, or marine, while supplemental glycine is obtained by synthesis or fermentation, which makes it compatible with a vegan diet — check the label for this information.
What we will not say is that one "replaces" the other for skin or joints. No claims exist for either glycine or collagen in this regard. If your concern is joint-related, glucosamine is another option; if your concern is overall protein intake, it is addressed with proteins.
What dose of glycine, when, and in what form?
Glycine is most often sold as a powder, which is logical for a molecule taken in grams rather than milligrams. It dissolves easily in cold water and its sweet taste makes it pleasant as is; it can also be added to a sugar-free drink, yogurt, or an evening infusion. Capsules exist, but many are needed to reach usual quantities.
Doses suggested by manufacturers generally range from 1 to 5 g per serving, with the 3 g portion being the most common. In the absence of an authorized claim, there is no official reference dose: what you read on a container is a suggestion, not a validated threshold. Start at the lower end of the range.
The most common time is in the evening, about thirty minutes before bedtime — this is the dominant use in compound formulas. Nothing dictates this slot if you take it for its amino acid contribution: it is then distributed indifferently throughout the day. At very high doses, the main reported inconvenience is digestive, and it is managed by fractioning the intake.
A usage tip, since we're talking about taste: glycine can be used to sweeten a bitter preparation, coffee, a shaker of essential amino acids, whose bitterness discourages many people. This is not a health property, it is a taste property, and it is very real.
Does glycine pose any danger?
It is an amino acid present in large quantities in common foods and in our own tissues, which places the subject far from risky molecules. At usual doses, tolerance is good, and reported adverse effects are primarily digestive: bloating, loose stools, gastric discomfort, especially beyond a few grams in a single dose. Slight drowsiness is sometimes mentioned in the evening.
Situations that require prior medical advice are classic: pregnancy and breastfeeding, due to lack of data; children and adolescents, this section being aimed at adults; renal or hepatic insufficiency, any additional nitrogen intake must be discussed; ongoing treatment affecting the central nervous system, as glycine has neurotransmitter activity; and any known metabolic disease concerning amino acid metabolism.
Finally, a remark that applies to all pages in this section: if your sleep is chronically degraded, no supplement will replace a doctor's diagnosis.
Frequently Asked Questions
What is the chemical formula for glycine?
C₂H₅NO₂, also written as NH₂-CH₂-COOH to show its structure: an amine group, a central carbon, a carboxylic acid group, and a single hydrogen atom as its side chain. Molar mass of approximately 75 g/mol.
Glycine: what is the definition?
In nutrition, glycine is the smallest of the twenty proteinogenic amino acids, non-essential because the body can synthesize it, with a sweet taste, and very abundant in collagen. The same word also refers to an ornamental climbing plant, with no connection whatsoever.
What is an amino acid, and is glycine an essential one?
An amino acid is a molecule combining an amine group and an acid group, which serves as a building block for proteins. An amino acid is called "essential" if the body cannot produce it and it must come from food — there are nine in adults, and glycine is not one of them. EAAs specifically refer to these essential amino acids.
What are the benefits of glycine?
The honest answer is twofold, and both are true at the same time. Biochemically, glycine is indispensable: one in three residues of collagen, one of the three constituents of glutathione, one of the three precursors of creatine, an inhibitory neurotransmitter of the nervous system. From a regulatory standpoint, no health claims are authorized in Europe for glycine: no one is allowed to announce that ingesting it produces such or such a benefit, and we will not do so any more than others. A seller who only gives you the first half of this answer is selling you a promise, not a product.
What is the composition of glycine powder?
Good glycine contains only one thing: glycine, declared at 99% or more, without flavor, without sweetener, without coloring, without anti-caking agent. It is one of the few products in the store whose ingredient list is a single word. If you read several, ask yourself what they are doing there — the powder is already naturally sweet, it doesn't need anything.
When should I take glycine?
In the evening, half an hour before bedtime, in the most common usage. For a simple amino acid intake, the timing is of little importance. In both cases, regularity matters more than the specific time.
Which glycine should I choose?
Three criteria are sufficient. The stated purity, and the presence of a certificate of analysis if the manufacturer publishes it. The form: powder, because a 3g dose would require six 500mg capsules. And the fineness of the grind, which determines dissolution: overly coarse glycine leaves a deposit at the bottom of the glass. The rest — synthetic or fermentation origin, presence of a measuring scoop — falls under comfort and your dietary constraints.
Is glycine toxic?
No, not the amino acid: it is a normal component of our proteins and diet, which the body produces itself every day, and the discomfort of an excess remains digestive. Be careful, however, with the homonym: the climbing plant, on the other hand, is toxic — its seeds and pods cause serious digestive problems if ingested, especially in children. This is one more reason not to confuse the two, and a case where a call to a poison control center is justified.
Is glycine beneficial for the skin?
What can be stated is limited to biochemistry: glycine is the most frequent residue of collagen, which is the major structural protein of the dermis. No European claim authorizes us to deduce an effect on the skin, and we will not do so. The collagen section addresses the topic in more detail.
Can it be combined with other supplements?
Yes, with no documented interactions at usual doses with common micronutrients. It is frequently found alongside magnesium — magnesium bisglycinate is nothing more than magnesium chelated with two glycine molecules — melatonin or ZMA. Simply add up the contributions.
What is the price of glycine?
It is one of the cheapest amino acids in the department, and the right benchmark is not the price of the jar but the price per gram. A 500g package taken at 3g represents approximately 165 servings: on a daily basis, the difference between two brands often comes down to a few cents. For equivalent purity, paying significantly more for glycine has no technical justification.
Where to buy glycine powder?
Here, or in our store. The point to check is the stated purity and the absence of superfluous additives: good glycine is a white powder, without added flavor or sweetener, as it is already sweet.
Glycine and sleep: what can be said?
That glycine is an inhibitory neurotransmitter, that evening formulas often contain it, and that no health claim authorizes advertising an effect on sleep. The only active ingredient in this category that has an official claim for falling asleep is melatonin, at 1 mg per dose.
What selection do we offer?
For such a simple compound, there aren't thirty criteria: glycine is judged by its purity, the fineness of its powder — which determines dissolution — and the honesty of its labeling. IO.Genix offers pure glycine powder, with no additives. Alongside it, our amino acid section includes glutamine and taurine, and our complete guide to sports nutrition explains how they work together.
An opinion in store near Montpellier?
In Vendargues, about ten minutes from Montpellier, our store can answer in two minutes a question that often lingers online: the real dose and how to take it. A three-gram powder is not measured with a tablespoon, and seeing the measuring scoop helps. We also ship throughout France and Europe. We will explain what glycine does in the body; we will not promise what no claim allows us to promise.
Sources: Ciqual for the amino acid composition of foods; EFSA for the register of authorized health claims, where glycine is not listed; ANSES for benchmarks related to food supplements.
Sources
- ANSES — Les compléments alimentaires
- Règlement UE n° 432/2012 — allégations de santé autorisées
- Règlement CE n° 1924/2006 — allégations nutritionnelles et de santé
À intégrer dans une alimentation variée et équilibrée et un mode de vie sain.
Questions fréquentes — L-Glycine
Quelle est la formule chimique de la glycine ?
C₂H₅NO₂, que l'on écrit aussi NH₂-CH₂-COOH pour faire apparaître sa structure : une fonction amine, un carbone central, une fonction acide carboxylique, et pour toute chaîne latérale un simple atome d'hydrogène. Masse molaire d'environ 75 g/mol.
Glycine : quelle définition ?
En nutrition, la glycine est le plus petit des vingt acides aminés protéinogènes, non essentiel car l'organisme sait le synthétiser, au goût sucré, très abondant dans le collagène. Le même mot désigne par ailleurs une plante grimpante ornementale, sans aucun lien.
Qu'est-ce qu'un acide aminé, et la glycine en est-elle un essentiel ?
Un acide aminé est une molécule associant une fonction amine et une fonction acide, qui sert de brique aux protéines. On dit « essentiel » celui que le corps ne sait pas fabriquer et qui doit venir de l'alimentation — il y en a neuf chez l'adulte, et la glycine n'en fait pas partie. Les EAA regroupent précisément ces acides aminés essentiels.
Quels sont les bienfaits de la glycine ?
Deux plans se répondent. Sur le plan biochimique, la glycine est incontournable : un résidu sur trois du collagène, l'un des trois constituants du glutathion, l'un des trois précurseurs de la créatine, un neurotransmetteur inhibiteur du système nerveux. Sur le plan réglementaire, aucune allégation de santé n'est autorisée en Europe pour la glycine : une étiquette conforme s'en tient donc à la composition et au mode d'emploi.
Quelle est la composition d'une glycine en poudre ?
Une bonne glycine ne contient qu'une seule chose : de la glycine, annoncée à 99 % ou plus, sans arôme, sans édulcorant, sans colorant, sans anti-agglomérant. C'est l'un des rares produits du magasin dont la liste d'ingrédients tient en un mot — la poudre étant déjà sucrée par nature, elle se passe d'additifs.
Quand prendre la glycine ?
Le soir, une demi-heure avant le coucher, dans l'usage le plus répandu. Pour un simple apport en acide aminé, le moment importe peu. Dans les deux cas, la régularité compte davantage que l'horaire.
Quelle glycine choisir ?
Trois critères suffisent. La pureté affichée, et la présence d'un certificat d'analyse si le fabricant le publie. La forme : la poudre, parce qu'une dose de 3 g demanderait six gélules de 500 mg. Et la finesse de la mouture, qui décide de la dissolution : une glycine trop grossière laisse un dépôt au fond du verre. Le reste — origine synthétique ou par fermentation, présence d'un dosage à la mesurette — relève du confort et de vos contraintes alimentaires.
Est-ce que la glycine est toxique ?
Non, pas l'acide aminé : c'est un constituant normal de nos protéines et de notre alimentation, que l'organisme fabrique lui-même chaque jour, et le désagrément d'un excès reste digestif. Attention en revanche à l'homonyme : la plante grimpante, elle, est toxique — ses graines et ses gousses provoquent des troubles digestifs sérieux en cas d'ingestion, notamment chez l'enfant. C'est une raison de plus de ne pas confondre les deux, et un cas où un appel au centre antipoison est justifié.
La glycine a-t-elle un intérêt pour la peau ?
Ce qui se dit s'arrête à la biochimie : la glycine est le résidu le plus fréquent du collagène, qui est la protéine structurale majoritaire du derme. Aucune allégation européenne n'existe sur ce terrain. Le rayon collagène traite le sujet de plus près.
Peut-on l'associer à d'autres compléments ?
Oui, sans interaction documentée aux doses usuelles avec les micronutriments courants. Elle se retrouve fréquemment à côté du magnésium — le bisglycinate de magnésium n'est d'ailleurs rien d'autre que du magnésium chélaté à deux molécules de glycine — de la mélatonine ou du ZMA. Additionnez simplement les apports.
Que trouve-t-on de glycine en poudre chez nous ?
Sur cette page, avec expédition partout en France et en Europe, et dans notre boutique de Vendargues près de Montpellier. Le point à vérifier est la pureté annoncée : une glycine correcte est une poudre blanche, sans arôme ni édulcorant ajouté, puisqu'elle est déjà sucrée.
Glycine et sommeil : que peut-on dire ?
Que la glycine est un neurotransmetteur inhibiteur, que les formules du soir en contiennent souvent, et qu'aucune allégation de santé n'autorise à annoncer un effet sur le sommeil. Le seul actif de ce pôle qui porte une allégation officielle sur l'endormissement est la mélatonine, à 1 mg par prise.
