{"product_id":"now-foods-glutathione-500mg","title":"Now Foods Glutathione 500mg - Reduced Glutathione Antioxidant Master","description":"\u003ch2\u003eWhat is Now Foods Glutathione 500 mg?\u003c\/h2\u003e\n\u003cp\u003eNow Foods Glutathione 500 mg is a supplement in vegetable capsules that brings together three ingredients. \u003cstrong\u003eOne capsule provides 500 mg of glutathione in its reduced form, 100 mg of milk thistle extract standardised to 80 mg of silymarin, and 50 mg of alpha-lipoic acid.\u003c\/strong\u003e The 120-capsule bottle covers four months.\u003c\/p\u003e\n\u003cp\u003eGlutathione is a tripeptide, meaning a small molecule made up of three amino acids: cysteine, glycine and glutamic acid. The body produces it itself, in all of its cells, and it plays a central role there in oxidation-reduction reactions. The so-called “reduced” form is the active form of the molecule, as opposed to its oxidised form.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe formula is built around a simple idea: rather than supplying glutathione on its own, it is paired with two ingredients that act in the same biochemical environment.\u003c\/strong\u003e Milk thistle is a plant traditionally associated with the liver; alpha-lipoic acid is a compound involved in cellular oxidation-reduction reactions. The rest of the American range can be browsed in our \u003ca href=\"\/en\/collections\/now-foods\"\u003eNow Foods\u003c\/a\u003e aisle, and alpha-lipoic acid, like glutathione, overlaps with the logic behind our \u003ca href=\"\/en\/collections\/coq-10\"\u003ecoenzyme Q10\u003c\/a\u003e aisle.\u003c\/p\u003e\n\n\u003ch2\u003eWhat does one capsule of Glutathione 500 mg contain?\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eComposition\u003c\/th\u003e\n\u003cth\u003ePer capsule\u003c\/th\u003e\n\u003cth\u003e% NRV\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlutathione (reduced form)\u003c\/td\u003e\n\u003ctd\u003e500 mg\u003c\/td\u003e\n\u003ctd\u003eNRV not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMilk thistle extract (\u003cem\u003eSilybum marianum\u003c\/em\u003e)\u003c\/td\u003e\n\u003ctd\u003e100 mg\u003c\/td\u003e\n\u003ctd\u003eNRV not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eof which silymarin\u003c\/td\u003e\n\u003ctd\u003e80 mg (80% strength)\u003c\/td\u003e\n\u003ctd\u003eNRV not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlpha-lipoic acid\u003c\/td\u003e\n\u003ctd\u003e50 mg\u003c\/td\u003e\n\u003ctd\u003eNRV not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eShell\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003eVegetable capsule (hypromellose)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePack size\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003e120 capsules, i.e. 120 days of use\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eWe have to start with the point that decides everything, and it is almost never written down: glutathione taken orally is very poorly absorbed.\u003c\/strong\u003e It is a tripeptide, and the digestive tract handles peptides the way it handles proteins: it breaks them apart. A significant share of the 500 mg swallowed is therefore split into amino acids before reaching the bloodstream. This is not a criticism of this product in particular, it is the problem faced by the entire category, and you deserve to know it before you buy.\u003c\/p\u003e\n\u003cp\u003eThat is also why another route exists and is favoured by many: supplying the body with the raw material it lacks so that it can make its own glutathione. That raw material is cysteine, and the supplement that provides it is called N-acetylcysteine. Our NAC aisle covers this approach, often for a smaller budget.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFrom a regulatory standpoint the situation is clear-cut: no health claim is authorised in Europe for glutathione, nor for alpha-lipoic acid, nor for milk thistle.\u003c\/strong\u003e Not for the liver, not for detoxification, not for oxidative stress, not for the skin. The dossiers submitted came to nothing. So we describe three molecules, their doses and how to use them, without announcing any outcome — and the word “detox”, which you will come across everywhere in this aisle, means nothing at all in regulatory terms.\u003c\/p\u003e\n\u003cp\u003eThe milk thistle strength is worth highlighting: 80 mg of silymarin per 100 mg of extract, i.e. 80%. That is a high strength, and it is the only line that allows two extracts of this plant to be compared. A product advertising “500 mg of milk thistle” without stating its silymarin content may contain ten times less.\u003c\/p\u003e\n\n\u003ch4\u003eIngredients list\u003c\/h4\u003e\n\u003cp\u003eGlutathione (reduced form), milk thistle extract (\u003cem\u003eSilybum marianum\u003c\/em\u003e, fruit and seeds) standardised to 80 mg of silymarin flavonoids, alpha-lipoic acid, hypromellose (vegetable capsule), microcrystalline cellulose, magnesium stearate of vegetable origin, silicon dioxide.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFree from wheat, gluten, soya, milk, egg, fish, shellfish, tree nuts and sesame.\u003c\/strong\u003e Produced in a facility that handles other ingredients containing these allergens.\u003c\/p\u003e\n\n\u003ch2\u003eHow should Glutathione 500 mg be taken?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDose:\u003c\/strong\u003e 1 capsule. \u003cstrong\u003eLiquid:\u003c\/strong\u003e a large glass of water. \u003cstrong\u003eTiming:\u003c\/strong\u003e in the morning on an empty stomach, 30 minutes before breakfast or 2 hours after a meal. \u003cstrong\u003eFrequency:\u003c\/strong\u003e one intake per day. \u003cstrong\u003eDuration:\u003c\/strong\u003e a course of 3 to 6 months, with periodic breaks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTaking it on an empty stomach is the essential instruction on this page, and it follows directly from what we have just explained.\u003c\/strong\u003e The less dietary protein there is in the stomach at the time of the intake, the less the digestive machinery is busy breaking peptides apart, and the better the chances of glutathione getting through intact. Thirty minutes before breakfast is the easiest slot to keep to day after day.\u003c\/p\u003e\n\u003cp\u003eIt is also the most demanding instruction: if you already take several supplements with meals, this one calls for a slot of its own. A routine you can sustain is worth more than a perfect routine abandoned after three weeks.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe manufacturer suggests pairing it with 250 to 500 mg of vitamin C.\u003c\/strong\u003e That is a biochemically coherent recommendation, since vitamin C and glutathione are involved in the same cellular cycles. Our \u003ca href=\"\/en\/collections\/vitamine-c\"\u003evitamin C\u003c\/a\u003e aisle offers doses suited to this pairing.\u003c\/p\u003e\n\u003cp\u003eKeep up a decent level of hydration through the day. The three-to-six-month course with periodic breaks is the schedule chosen by the manufacturer; the 120-capsule bottle covers four months in one go, which corresponds to a complete course with no need to reorder along the way. The product combines without any overlap with a \u003ca href=\"\/en\/collections\/curcumin\"\u003eturmeric\u003c\/a\u003e or an \u003ca href=\"\/en\/collections\/omega-3\"\u003eomega 3\u003c\/a\u003e, those being taken with meals.\u003c\/p\u003e\n\n\u003ch2\u003eWho is Glutathione 500 mg for, and who is it not for?\u003c\/h2\u003e\n\u003cp\u003eIt is aimed at an adult who is looking for this molecule specifically and who knows its absorption limits. It is a niche product, not a general-purpose supplement, and it should not be a first purchase.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTwo contraindications appear explicitly on the packaging.\u003c\/strong\u003e The first: \u003cstrong\u003eallergy to Asteraceae\u003c\/strong\u003e, the botanical family of milk thistle, which also includes mugwort, chamomile and ragweed. The second: \u003cstrong\u003echemotherapy treatment\u003c\/strong\u003e, for which medical advice is essential before taking anything — high-dose antioxidants may interfere with certain protocols, and that question is not one to settle over the counter.\u003c\/p\u003e\n\u003cp\u003eIt is reserved for adults, and a healthcare professional must be consulted in the event of pregnancy, breastfeeding, medical treatment or a health problem.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat you should not expect from it, and this is the heart of the matter.\u003c\/strong\u003e It does not “detoxify” anything: the liver and kidneys do that work constantly, without outside help, and the word has no medical definition. It does not lighten the skin — that is a widespread use elsewhere in the world, with no authorised claim in Europe and no solid data by the oral route. It does not improve sporting performance. You will not feel anything when you take it, and that is normal. Any question concerning your liver is a matter for a blood test and a doctor.\u003c\/p\u003e\n\n\u003ch2\u003eGlutathione or N-acetylcysteine?\u003c\/h2\u003e\n\u003cp\u003eThis is the comparison that genuinely matters in this aisle, and it deserves a straight answer even if it does not favour the sale.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGlutathione taken orally runs into an obstacle: it is a tripeptide, and the digestive tract breaks most of it apart before it reaches the bloodstream.\u003c\/strong\u003e You are supplying the finished molecule, but only a fraction arrives intact. That is the structural limit of this category.\u003c\/p\u003e\n\u003cp\u003eN-acetylcysteine tackles the problem from the other end: it supplies cysteine, the amino acid that limits the body's own production of glutathione. It is well absorbed, it costs less, and the logic is more solid. For most situations, that is the choice we recommend first, and our \u003ca href=\"\/en\/collections\/nac\"\u003eNAC\u003c\/a\u003e aisle covers it.\u003c\/p\u003e\n\u003cp\u003eIn which case does this product remain relevant? When it is this precise formula you are after, with the milk thistle and alpha-lipoic acid pairing, and the absorption question does not put you off. If your goal is more general, our \u003ca href=\"\/en\/collections\/multivitamines\"\u003emultivitamins\u003c\/a\u003e aisle covers a broad need, and our \u003ca href=\"\/en\/collections\/vitamine-e\"\u003evitamin E\u003c\/a\u003e aisle offers the only antioxidant approach in this catalogue to have an authorised claim.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003ch3\u003eWhat exactly does one capsule contain?\u003c\/h3\u003e\n\u003cp\u003e500 mg of reduced glutathione, 100 mg of milk thistle extract standardised to 80 mg of silymarin, and 50 mg of alpha-lipoic acid. The shell is a vegetable capsule made of hypromellose. The bottle holds 120 of them, i.e. four months at one a day.\u003c\/p\u003e\n\u003ch3\u003eIs glutathione well absorbed by the oral route?\u003c\/h3\u003e\n\u003cp\u003eNo, and that is the major limit of this category. It is a tripeptide, which the digestive tract breaks apart in large part before it reaches the bloodstream. That is why many people prefer N-acetylcysteine, which supplies the raw material for the body to make it itself.\u003c\/p\u003e\n\u003ch3\u003eWhy take it on an empty stomach?\u003c\/h3\u003e\n\u003cp\u003eTo limit competition with dietary proteins: the fewer peptides the stomach has to handle, the better the chances of glutathione getting through intact. Thirty minutes before breakfast, or two hours after a meal, are the two slots chosen by the manufacturer.\u003c\/p\u003e\n\u003ch3\u003eDoes this product detoxify the body?\u003c\/h3\u003e\n\u003cp\u003eNo, and the word has no medical definition. The liver and kidneys deal with the elimination of waste constantly, without outside help. No claim of this kind is authorised in Europe for glutathione, milk thistle or alpha-lipoic acid.\u003c\/p\u003e\n\u003ch3\u003eWhat is the milk thistle for in the formula?\u003c\/h3\u003e\n\u003cp\u003eIt is a plant traditionally associated with the liver, standardised here to 80 mg of silymarin per 100 mg of extract, i.e. 80%. That is a high strength and it is the only line that allows two extracts to be compared. No claim is authorised in Europe for this plant, however.\u003c\/p\u003e\n\u003ch3\u003eAre there any contraindications?\u003c\/h3\u003e\n\u003cp\u003eTwo appear on the packaging: allergy to Asteraceae, the family of milk thistle, and chemotherapy treatment, for which medical advice is essential. Also consult a healthcare professional in the event of pregnancy, breastfeeding or ongoing treatment.\u003c\/p\u003e\n\u003ch3\u003eAre the capsules suitable for vegans?\u003c\/h3\u003e\n\u003cp\u003eThe shell is a vegetable capsule made of hypromellose and the magnesium stearate is of vegetable origin. The manufacturer declares the absence of wheat, gluten, soya, milk, egg, fish, shellfish, tree nuts and sesame, but points out that manufacturing takes place in a facility handling these allergens.\u003c\/p\u003e\n\n\u003ch2\u003eWhere can you buy Now Foods Glutathione 500 mg?\u003c\/h2\u003e\n\u003cp\u003eThe 120-capsule bottle can be ordered from this page, and we ship throughout France and Europe. At the Vendargues shop, about ten minutes from Montpellier, we always start by explaining the absorption question before selling this product. Many customers leave with N-acetylcysteine, which costs less and rests on more solid logic; those who stick with glutathione then know why. The rest of the aisle can be browsed in our \u003ca href=\"\/en\/collections\/nutrition-sportive\"\u003esports nutrition\u003c\/a\u003e selection.\u003c\/p\u003e","brand":"NOW FOODS","offers":[{"title":"Default Title","offer_id":52334703214919,"sku":"PWB-P45734","price":49.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0881\/9467\/9111\/files\/Now-Foods-Glutathione-500mg-Antioxydant-Maitre-Detox-carre.png?v=1788602542","url":"https:\/\/kissnutrition.fr\/en\/products\/now-foods-glutathione-500mg","provider":"KISS NUTRITION","version":"1.0","type":"link"}